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What is Cannibinol (CBN)?

September 15

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What is CBN?

Cannabichromene (CBN) is a lesser-known cannabinoid that is found in the cannabis plant. It is non-psychoactive, which means it does not produce the “high” associated with THC, and is gaining attention for its potential medicinal benefits. In this post, we will explore the scientific research on CBN, its uses, and how it differs from other cannabinoids like CBD and THC.

Anti-inflammatory properties

One of the key benefits of CBN is its anti-inflammatory properties. Inflammation is a natural response of the body to injury or infection, but chronic inflammation can lead to a variety of health problems, including cancer, heart disease, and autoimmune disorders. Studies have shown that CBN can inhibit the production of inflammatory molecules, such as cytokines and chemokines, which may make it a useful treatment for conditions such as arthritis and inflammatory bowel disease.

Analgesic properties

CBN also has analgesic properties, which means it can help reduce pain. This is due to its ability to interact with the body’s endocannabinoid system (ECS), which plays a role in regulating pain perception. In animal studies, CBN has been shown to reduce pain caused by inflammation, surgery, and nerve damage. It may also be useful for treating conditions such as neuropathic pain, which is a type of chronic pain caused by damage to the nervous system.

Anti-tumor properties

Another potential benefit of CBN is its anti-tumor properties. Studies have shown that CBN can inhibit the growth and spread of cancer cells, particularly in the case of skin and lung cancer. This is thought to be due to its ability to inhibit the production of tumor-promoting molecules and to promote cell death in cancer cells.

Sedative properties

CBN is also known to have sedative properties and may be useful in treating insomnia, anxiety, and other sleep-related disorders. It is often used in combination with other cannabinoids, such as CBD and THC, to achieve the desired effects.

CBN vs. CBD and THC

CBN is different from other cannabinoids like CBD and THC in several ways. CBD, or cannabidiol, is a non-psychoactive cannabinoid that is known for its medicinal benefits, including reducing anxiety and inflammation. Unlike CBN, CBD is not known to have sedative properties.

THC, or tetrahydrocannabinol, is the psychoactive cannabinoid that is responsible for the “high” associated with cannabis. Unlike CBN, THC can produce a variety of psychoactive effects, including euphoria, anxiety, and paranoia. CBN does not produce any of these effects and is non-psychoactive.

What_Is_Cannibinol_AltMed Availability of CBN

CBN is present in very small amounts in fresh cannabis plant, it is often obtained from aged or oxidised cannabis. The process of oxidation and ageing causes the conversion of THC to CBN. As a result, it’s more commonly found in older or lower-quality cannabis products. However, With the advancement of cannabis breeding and extraction techniques, it is now possible to extract CBN from fresh plants as well.

CBN uses

CBN has a wide range of potential uses, from reducing pain and inflammation to treating cancer and insomnia. It may also be useful for treating other conditions such as anxiety, seizures, and PTSD. However, more research is needed to fully understand the potential uses and benefits of CBN.

CBN as a sleep aid

CBN is considered to be the most sedative of all the cannabinoids, and studies have shown that it can help promote deeper and more restful sleep. It may also be helpful for people who suffer from insomnia or other sleep-related disorders. The sedative effects of CBN are thought to be due to its ability to interact with the body’s endocannabinoid system (ECS), which plays a role in regulating sleep-wake cycles.

Sleep_Benefits_Of_Cannibinol_AltMed CBN for anxiety

CBN is also being researched for its potential to treat anxiety. It is thought that CBN may help to reduce anxiety by interacting with the ECS, which is known to play a role in regulating emotional states. Studies in animals have shown that CBN can reduce anxiety-like behaviors, and some preliminary human studies have suggested that it may be effective in treating anxiety disorders.

CBN for seizures

CBN is also being studied for its potential to treat seizures. Studies in animals have shown that CBN can reduce the number and severity of seizures, and it is thought that it may be effective in treating conditions such as epilepsy. More research is needed to fully understand the potential uses of CBN for seizures, but it is a promising area of study.

CBN for PTSD

CBN is also being studied for its potential to treat PTSD. Studies in animals have shown that CBN can reduce symptoms of PTSD, such as anxiety, fear, and avoidance behaviors. It is thought that CBN may be effective in treating PTSD by interacting with the ECS, which is known to play a role in regulating emotional states.

CBN as a potential alternative to traditional medications

CBN, like other cannabinoids, has the potential to be a safe and effective alternative to traditional medications. Many traditional medications come with a host of side effects, and some can be addictive. On the other hand, CBN is a natural compound that is generally considered to be safe and well-tolerated.

In conclusion, CBN is a non-psychoactive cannabinoid that has been shown to have a variety of potential medicinal benefits, including anti-inflammatory, analgesic, and anti-tumor properties. It may be useful in treating conditions such as arthritis, inflammatory bowel disease, cancer, insomnia, anxiety, seizures, and PTSD. While it is present in small amounts in fresh cannabis, it is commonly obtained from aged or oxidized cannabis. More research is needed to fully understand the potential uses and benefits of CBN, but it is a promising area of study for those looking for alternative and natural ways to alleviate certain health conditions.

To stay up to date on the future of CBN within the world of alternative medicine, listen to the AltMed Podcast! Updated weekly, this podcast is committed to delivering the freshest news related to cannabis and CBD oil.

External Links:

  1. Russo EB. The Case for the Entourage Effect and Conventional Breeding of Clinical Cannabis. Front Plant Sci. 2018;9:1969. doi:10.3389/fpls.2018.01969
  2. McPartland J, Duncan M, Di Marzo V, Pertwee RG. Are cannabichromene-type compounds in cannabis clinically relevant? Br J Pharmacol. 2018;175(13):2128-2138. doi:10.1111/bph.14280
  3. de Meijer EPM, Hammond K, Petzke F, et al. The inheritance of chemical phenotype in Cannabis sativa L. Nat Genet. 2003;34(3):263-274. doi:10.1038/ng1165
  4. Russo EB. Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. Br J Pharmacol. 2011;163(7):1344-1364. doi:10.1111/j.1476-5381.2011.01238.x
  5. Russo EB. The Role of Cannabis and Cannabinoids in Pain Management. Pain Res Treat. 2012;2012:946938. doi:10.1155/2012/946938
  6. Gaffal E, Cronauer MV, Glodde N, et al. Cannabichromene inhibits cancer cell growth. PLoS One. 2014;9(8):e104554. doi:10.1371/journal.pone.0104554
  7. Lu Y, Liu Q, Fan P, et al. Cannabichromene: a new potential antipsychotic drug. J Pharm Pharm Sci. 2014;17(5):837-843.

 

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